ارزش تشخیص زمان واکنش ساده و انتخابی در تفکیک بیماران مبتلا به مالتیپل اسکلروزیس از افراد بهنجار

نوع مقاله : مقاله پژوهشی

نویسندگان

1 دانشجوی دکترای روانشناسی، دانشگاه اصفهان، اصفهان، ایران

2 دکترای پسیکوفارماکولوژی، دانشیارگروه روانشناسی، دانشگاه اصفهان، اصفهان، ایران.(نویسنده مسئول)

3 دکترای روانشناسی، استادیار گروه روانشناسی، دانشگاه گیلان، رشت، ایران.

4 متخصص مغز و اعصاب، استاد دانشگاه علوم پزشکی، دانشگاه علوم پزشکی گیلان، رشت، ایران

چکیده

مقدمه
بیماری­هایی که سیستم عصبی مرکزی را تخریب می­کنند، می­توانند موجب اختلال در عملکردهای شناختی شوند. یکی از روش­های آگاهی از رابطه­ی مغز با افکار و رفتار، مطالعه­ی مغز افرادیست که سیستم عصبی مرکزی­شان آسیب دیده است و در میان آنها یکی از شایع­ترین این بیماری­ها مالتیپل­اسکلروزیس است.
روش کار
هدف از پژوهش حاضر بررسی ارزش تشخیصی زمان واکنش ساده و انتخابی در تفکیک بیماران مبتلا به مالتیپل اسکلروزیس (MS) از افراد بهنجار بوده است. بدین منظور دو گروه متشکل از 44 بیمار مبتلا به مالتیپل­اسکلروزیس و 48 فرد بهنجار انتخاب شده، زمان واکنش ساده و انتخابی آن‌ها اندازه­گیری، سپس اطلاعات جمعیت­شناختی  آزمودنی­ها جمع­آوری، میزان ناتوانی بیماران با استفاده از مقیاس میزان ناتوانی گسترش­یافته­ی کورتزک (EDSS) ارزیابی شد. زمان واکنش ساده و انتخابی بیماران با نرم­افزار واکنش­سنج  مورد سنجش قرار گرفت. به منظور تحلیل داده­ها از آزمون­های من­ویتنی و مدل رگرسیون لجستیک همزمان در SPSS-26 استفاده شد.
نتایج
زمان واکنش ساده (0.011=z= -2.556, p ) و انتخابی (0.001>z=-6.348, p) در بیماران MS به طورمعناداری از گروه گواه بیشتر بود و بخوبی توانست مبتلایان به ام اس را از افراد سالم تفکیک نماید. زمان واکنش انتخابی به لحاظ آماری پیش­بینی­کننده­ی مطلوبی برای وضعیت سلامتی و بیماری بود.
نتیجه گیری
بر اساس یافته های پژوهش زمان واکنش در حالت­های ساده و انتخابی، روش مناسبی برای تمایز  بیماران مبتلا به MS از افراد سالم است و می توان در وضعیت های بالینی اعم از درمانگاه ها و بخش های مغز و اعصاب از آن بهره گرفت.

کلیدواژه‌ها

عنوان مقاله [English]

Diagnostic value of simple and selective Reaction Time in discriminating patients with multiple sclerosis from normal people

نویسندگان [English]

  • Faeze Khanlarzade 1
  • Karim Asgari 2
  • Sajjad Rezaei 3
  • Alia Saberi 4
1 Ph.D Student of Psychology, Faculty of Education and Psychology, University of Isfahan, Isfahan, Iran.
2 Associate professor of Psychopharmacology, Faculty of Education and Psychology, University of Isfahan, Isfahan, Iran.(Corresponding Author)
3 Assistant Professor, Department of Psychology, University of Guilan, Rasht. Iran.
4 Professor, Department of Neurology, Guilan University of Medical Science, Rasht, Iran.
چکیده [English]

Introduction
Cognitive dysfunctions may be brought about following the diseases which have destructive effects on the central nervous system. One way of studying the relationship among brain, behavior and thought, is examining and investigating the brain damaged people, among them Multiple sclerosis is one of the most prevalent diseases of CNS.
Material and Method
The aim of present study was to investigate the diagnostic value of simple and selective reaction time in discriminating patients with multiple sclerosis (MS) from normal people. For that purpose, two groups of patient with MS (n=44), a group of normal people (n=48) were selected as the control group. Their reaction time in simple and selective modes were measured by reaction timer, then demographic information of all subjects were collected and their inability was evaluated by EDSS.
Mann-Withney U test and logistic regression were used to analyze the data. Results:Following analysis of data, it was revealed that both simple (z= -2.566, p=0.011) and selective (z=6.348, p<0.001) modes of reaction time in patients with MS, were significantly more than control group. Selective reaction time was statistically able to predict health and illness (χ2= 51.067, df= 2, p<0.0001).
Results
Both simple and selective reaction times were significantly longer in the patient group, and it was able to differentiate the MS patients from normal people.
Conclusion
According to the findings of the research, reaction time in both simple and selective modes is appropriate in differentiating the patient with MS, from normal people, and hence it is worthy to be utilized in clinical situations including clinics and neurology wards of hospitals.

کلیدواژه‌ها [English]

  • simple reaction time
  • selective reaction time
  • multiple sclerosis

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مجله دانشکده پزشکی دانشگاه علوم پزشکی مشهد
دوره 66، شماره 3
مرداد-شهریور1402
مرداد و شهریور 1402
صفحه 400-414

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