بررسی تأثیر تمرین ورزشی و مکمل سازی زعفران (.Crocus sativus L) بر مقادیر سرمی نیتریک اکساید و عملکرد نعوظ در مردان چاق مبتلا به دیابت نوع دو

نوع مقاله : مقاله پژوهشی

نویسندگان

1 استادیار، گروه فیزیولوژی ورزشی، دانشکده‌ی علوم ورزشی، دانشگاه فردوسی مشهد، مشهد، ایران

2 استاد، گروه فیزیولوژی ورزشی، دانشکده‌ی علوم ورزشی، دانشگاه فردوسی مشهد، مشهد، ایران

3 استاد، گروه فیزیولوژی ورزشی، دانشکده‌ی علوم ورزشی و تندرستی، دانشگاه تهران، تهران، ایران

4 دانشکده‌ی تغذیه و رژیم‌درمانی، دانشگاه آکادیا، کانادا

چکیده

مقدمه: دیابت نوع دو و چاقی با کاهش عملکرد عروق و ایجاد اختلال در نعوظ موجب نقص عملکرد جنسی در مردان می‌شود. هدف از پژوهش حاضر، بررسی اثر مستقل و تعاملی 12 هفته تمرین ورزشی و مکمل سازی زعفران بر مقادیر سرمی نیتریک اکساید و عملکرد نعوظ در مردان چاق مبتلابه دیابت نوع دو بود.
روش‌ کار: در این پژوهش نیمه تجربی تعداد 60 مرد چاق مبتلا به دیابت نوع دو به شکل تصادفی در چهار گروه 15 نفره 1) تمرین 2) زعفران 3) تمرین + زعفران 4) کنترل قرار گرفتند. آزمودنی‌های گروه اول و سوم به مدت 12 هفته به اجرای پروتکل تمرین ورزشی (مقاومتی+ هوازی) پرداختند. همچنین آزمودنی‌های گروه دوم و سوم روزانه یک عدد قرص 100 میلی‌گرمی زعفران و گروه اول به همین مقدار دارونما دریافت کردند. نمونه‌ی خونی و پرسش‌نامه‌ی مربوطه در دو مرحله‌ی پیش و پس‌آزمون جهت سنجش مقادیر بیوشیمیایی و عملکرد نعوظ جمع‌آوری شد. داده‌ها با استفاده از آزمون‌ تی همبسته، آنالیز واریانس یک‌طرفه و آزمون تعقیبی توکی در سطح معناداری کمتر از 05/0 تجزیه‌وتحلیل شد.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

Investigation of the effect of combined training and saffron (Crocus sativus L.) supplementation on serum levels of nitric oxide and erectile function in obese men with type 2 diabetes

نویسندگان [English]

  • Babak Hooshmand Moghadam 1
  • Amir Rashidlamir 2
  • Seyyed Reza Attarzadeh Hosseini 2
  • Abbas Ali Gaeini 3
  • Mojtaba Kaviani 4
1 Assistant Professor, Department of Exercise Physiology, Faculty of Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran.
2 Professor, Department of Exercise Physiology, Faculty of Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran.
3 Professor, Department of Exercise Physiology, Faculty of Sports and Health Sciences, University of Tehran, Tehran, Iran.
4 Professor, School of Nutrition and Dietetics, Acadia University, Canada.
چکیده [English]

Introduction: Type 2 diabetes and obesity cause sexual dysfunction in men by reducing vascular function and erectile dysfunction. The aim of the present study was to investigate the independent and interactive effect of 12 weeks of combined training and saffron supplementation on serum levels of nitric oxide and erectile function in obese men with type 2 diabetes.
Materials and Methods: In this quasi-experimental study, 60 obese men with type 2 diabetes (age: 39.51±5.02) were randomly divided into four groups: 1) combined training 2) saffron 3) combined training + saffron 4) control. The subjects of the first and third groups performed a combined training protocol (resistance + aerobics) for 12 weeks. Also, the subjects of the second and third groups received one pill of 100 mg of saffron daily and the first group received the same amount of placebo. Blood samples and related questionnaire were collected in two stages of pre-and post-test to measure the biochemical values and erectile function. Data were analyzed using paired t-test, one-way ANOVA, and Tukey's post hoc test at a significance level of less than 0.05.
5).

کلیدواژه‌ها [English]

  • Physical activity
  • Saffron
  • Sexual function
  • Diabetes

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مجله دانشکده پزشکی دانشگاه علوم پزشکی مشهد
دوره 67، شماره 6
بهمن-اسفند1403
بهمن و اسفند 1403
صفحه 1525-1537

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