Document Type : Research Paper
Authors
1
PhD student, Department of exercise physiology, Bo. C., Islamic Azad University, Borujerd, Iran.
2
Assistant Professor, Department of Physical Education and Sports Sciences, Khor.C., Islamic Azad Univercity, Khorramabad, Iran
3
Associate Professor, Sports Sciences Department, Faculty of Literature and Human Sciences, Lorestan University, Khorramabad, Iran
4
Assistant Professor, Departement of Motor Behavior, Bo. C., Islamic Azad University, Borujerd, Iran.
10.22038/mjms.2025.88315.5021
Abstract
Introduction:Chronically toxic cadmium, in addition to affecting the immune system and inflammatory markers, can affect the transmission pathway and development of pain tolerance. In contrast, exercise and pollen protect the immune, inflammatory, and nervous systems. The aim of the present study was to investigate the interactive effect of high-intensity interval training and pollen consumption on some inflammatory factors and pain tolerance threshold in the hippocampus of rats exposed to cadmium.
Material& Methods:In this experimental study, 25 male rats were randomly divided into 5 groups: healthy control, cadmium, pollen, high-intensity interval training, and pollen-high-intensity interval training. They performed high-intensity interval training for8 weeks, 3days a week. They simultaneously consumed cadmium chloride(40 mg/kg/w/d) and pollen(200 mg dissolved in 2.4cc of normal saline)daily. Pain threshold was measured by hot plate test and interleukin-1 beta and tumor necrosis factor-alpha were measured by ELISA.Two-way analysis of variance, an independent t-test at a significance level of P<0.05 was used for data analysis.
Results:The main effect of high-intensity interval training and pollen was not significant for inflammatory factors (p>0.05).The interaction effect of training and pollen was not significant for IL-1β (p=0.227) and TNF-α (p=0.846).The main effect of training(p=0.067) and the interaction effect of training and pollen for the tolerance threshold did not show a significant increase (p=0.095), but the main effect of pollen was significant (p=0.001).
Conclusion:High-intensity interval training combined with bee pollen consumption was unable to improve inflammatory factors and pain threshold in rats exposed to cadmium. However,bee pollen may be able to increase pain tolerance.
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