ارزیابی تظاهرات نورولوژیک آنفلوانزا A(H1N1)در کودکان بستری با شک به آنفولانزا در بیمارستان قدس

نوع مقاله : مقاله پژوهشی

نویسندگان

دانشکده پزشکی، دانشگاه علوم پزشکی قزوین، قزوین، ایران

10.22038/mjms.2026.80182.4624

چکیده

ظهور آنفولانزای A (H1N1) با افزایش گزارش تظاهرات عصبی در کودکان مواجه شد. این مطالعه با هدف تعیین تظاهرات نورولوژیک آنفلوانزا A(H1N1)در کودکان بستری در بیمارستان صورت گرفت.
مواد و روش ها: در این مطالعه گذشته نگر جامعه آماری شامل کلیه بیماران مبتلا به آنفلوانزا بستری در بیمارستان قدس در بازه زمانی 2017 الی 2019 که دارای معیار ورود به مطالعه شامل داشتن علائم مبتنی بر آنفولوآنزا، و تست مثبت pcr ، وارد مطالعه شدند. کلیه اطلاعات دموگرافی و بالینی بیماران اخذ و در چک لیست محقق ساخته ثبت گردید. تمامی اطلاعات با استفاده از نرم افزار spss ورژن 26 مورد تجزیه و تحلیل آماری قرار گرفت.
نتایج: 130 بیمار وارد مطالعه شده که 4/65 % پسر با میانگین سنی 51.2 ماه مشخص شد. شایع ترین علامت بالینی به ترتیب تب، سرفه، تهوع و استفراغ و ضعف و بی حالی بود. در 4 کودک مورد بررسی نیز علائم به نفع Raise ICP مشاهده گردید. 29 کودک دچار تشنج با بیشترین تظاهرات به شکل حرکات تونیک کلونیک ژنرالیزه، UWGکه 26 مورد آن با تب همراهی داشت. بیشترین یافته در گزارشات آزمایشگاهی نیز به ترتیب گلوکز و CRP افزایش یافته، وجود گلبول قرمز و گلبول سفید در مایع مغزی نخاعی بود. 4 نفر (3 %) از کودکان در بدو ورود دچار کاهش سطح هوشیاری بوده اند و متاسفانه 3 کودک نیز Expired شدند.
بحث و نتیجه گیری: در صورت بروز همزمان علائم نورولوژیک و علائم عفونت تنفسی آزمون تشخیصی آنفلوانزا و به دنبال آن شروع درمان ضد ویروسی ضروری می باشد.

کلیدواژه‌ها

موضوعات


عنوان مقاله [English]

Evaluation of neurological manifestations of influenza A(H1N1) in children hospitalized with suspected influenza in Qods Hospital

نویسندگان [English]

  • Hossein Farshadmoghadam
  • pourandokht gholamipour shirazi
  • zahra pirzadeh
  • alireza hajisoleimani
Qazvin University Medical Science
چکیده [English]

The emergence of influenza A (H1N1) was accompanied by an increase in reports of neurological manifestations in children. This study aimed to determine the neurological manifestations of influenza A(H1N1) in hospitalized children.
Materials and methods: In this retrospective study, the statistical population, including all patients with influenza admitted to Quds Hospital between 2017 and 2019, who met the inclusion criteria of having symptoms based on influenza, and a positive PCR test, were included in the study. All the demographic and clinical information of the patients were collected and recorded in the researcher's checklist. All information was statistically analyzed using spss version 26 software.
Results: 130 patients were included in the study, of which 65.4% were boys with an average age of 51.2 months. The most common clinical symptoms were fever, cough, nausea and vomiting, and weakness and lethargy, respectively. In 4 examined children, symptoms in favor of Raise ICP were observed. 29 children had convulsions with the most manifestations in the form of generalized tonic-clonic movements, UWG, 26 of which were accompanied by fever. The most common findings in the laboratory reports were increased glucose and CRP respectively, and the presence of red blood cells and white blood cells in the cerebrospinal fluid. 4 people (3%) of the children had a reduced level of consciousness upon arrival, and unfortunately 3 children also expired.
In case of simultaneous occurrence of neurological symptoms and symptoms of respiratory infection, a diagnostic test for influenza is necessary, followed by the initiation of antiviral treatment.

کلیدواژه‌ها [English]

  • Influenza A (H1N1)
  • neurological manifestations
  • encephalopathy
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