The present study was conducted to investigate the effectiveness of mindfulness training on loneliness and work-family conflict among satellite and headquarters employees of the Iranian Offshore Oil Company. The current study was a semi-experimental application with a pre-test-post-test design with a control group and a two-month follow-up period. In this study, the statistical population included 7,300 official, male and female employees of the Offshore Oil Company in the first six months of 2024. In this research, 64 peaple were selected by purposeful sampling and randomly assigned to experimental and control groups (32 people in the experimental and 32 people in the control group). Employees in the experimental group received mindfulness training for ten weeks. In this study, the Feeling Loneliness Questionnaire (FLQ) and the Work-Family Conflict Questionnaire (WFCQ) were used. The data were analyzed through mixed ANOVA via SPSS23 software. The results showed that mindfulness training has significant effect on the loneliness (p<0.0001) and work-family conflict (p<0.0001) in satellite and headquarters employees of the Iranian Offshore Oil Company. Based on the results of the present study, mindfulness training, by developing awareness of body sensations, improving the quality of communication, teaching how to consciously deal with unpleasant emotions, and teaching how to observe thoughts as transient mental events, can be considered an effective method in reducing feelings of loneliness and work-family conflict among satellite and headquarters employees of the Iranian Offshore Oil Company.