نوع مقاله : مقاله پژوهشی
نویسندگان
1 دانشیار گروه قلب و عروق، دانشگاه علوم پزشکی مشهد، مشهد، ایران
2 دانشجوی پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران
چکیده
کلیدواژهها
عنوان مقاله [English]
نویسندگان [English]
Abstract:
Introduction: Prevalence of cardiovascular disease in diabetic patients is more than general population and its adverse events are more common, though multiple different protocol of glucose control in acute coronary syndrome were proposed , in this study two different protocol of controlling blood sugar level for decreasing hospital adverse events were compared.
Method:
200 diabetic patients with acute coronary syndrome in Imam Reza Cardiology Department after 48 hours insulin therapy randomly divided in to two groups: intensive control, in this group we checked blood glucose level before meal and two hours post prandial (6 times a day) and insulin depending on chart with target fasting glucose70-110 mg/dl and two hours post prandial lower than 180 mg/dl. second group was conventional control with checking fasting blood glucose level daily, with using the diabetes treatment like before admission with target of fasting glucose 70-130 mg/dl. All patients have been visited daily and major adverse cardiac (MACE) events were recorded.
Results:
Overall 12% of all patients had recurrent ischemia (10% of intensive group versus 14% in conventional group, p=0.0514), Reinfarction in one patient of conventional group (p=1.000), arrhythmia in 5 patients (2.5%), 3 patients (3%) of conventional group versus 2 patients(2%) of intensive group (p=1.000), ventricular dysfunction in 85% of patients, 84 patients (84%) of intensive group versus 86 patients (86%) of conventional group (p=0.843)
and intra hospital mortality rate was 4%, 5 patients (5%) in conventional versus 3 patients (3%) in intensive group, (p=0.721).
Conclusion: depending on the study we didn’t find any significant differences in major adverse cardiac events in two groups .
کلیدواژهها [English]
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