نوع مقاله : مقاله پژوهشی
1 - دانشیار روماتولوژی، دانشگاه علوم پزشکی مشهد، مشهد، ایران
2 - استادیار نفرولوژی، دانشگاه علوم پزشکی مشهد، مشهد، ایران
3 استاد نفرولوژی، دانشگاه علوم پزشکی مشهد، مشهد، ایران
4 پزشک خانواده، دانشگاه علوم پزشکی مشهد، مشهد، ایران
عنوان مقاله [English]
Renal biopsy plays a very important role in diagnosis, and treatment of patients with systemic lupus erythematosus (SLE). The purpose of our study was to assess the role of renal biopsy in determining the prognosis of SLE.
Materials and Methods
In this prospective review, which was pereformed in the Department of Internal Medicine of Gheam Medical Center, we studied 34 SLE patients for 5 years. After acquiring medical history and a routine general physical examination, clinical and serological characteristics of all patients were consecutively collected in questionnaires.
Of 34 patients, 32 were female and 2 were male. The median age of patients was 25.12±12.05 years. All of them had lupus nephritis. The most common type of renal pathology was class IV lupus nephritis. Patients with class IV lupus nephritis had the worst prognosis.
Age, sex and renal pathology prevalence in the present study is similar to other studies. Lupus nephritis remains a strong predictor for development of end-stage renal disease (ESRD) and death in patients with SLE.