نوع مقاله : مقاله پژوهشی
نویسندگان
گروه تربیت بدنی وعلوم ورزشی ، واحد قائمشهر، دانشگاه آزاد اسلامی، قائمشهر، ایران
چکیده
کلیدواژهها
عنوان مقاله [English]
نویسندگان [English]
Introduction: Type 2 diabetes is a multifactorial disease, with both genetic and environmental factors influencing its prevalence. The aim of this experimental study was to determine the effect of 6 weeks of resistance training on GLP1 expression in pancreatic tissue as well as glucose and insulin levels in type 2 diabetic rats.
method: The statistical population consisted of all male Wistar rats of Pasteur Institute of Iran, from which 14 10-week-old rats weighing 220 ± 20 g were purchased. The studied rats were exposed to 6 weeks of high-fat diet and STZ injection of type 2 diabetes and were randomly divided into two groups (control and resistance). The resistance group then participated in a resistance training course for 6 weeks with 5 sessions per week. 48 hours after the last training session, fasting glucose and insulin levels and GLP1 expression in pancreatic tissue of both groups were measured and compared by independent t-test. All statistical analyzes were performed using SPSS / Win software version 16.
Results: Resistance training improved fasting glucose levels compared to the control group. Serum insulin levels and GLP1 expression in pancreatic tissue of the resistance group increased significantly compared to the control group. Significant level of α = % 5 was considered.
Conclusion: Based on the findings of this study, increased serum insulin in response to resistance training in T2D rats may be attributed with increased Mafa expression in pancreas tissue.
کلیدواژهها [English]
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