نوع مقاله : مقاله پژوهشی
نویسندگان
1 دانشیار، گروه بیماریهای عفونی، دانشگاه علوم پزشکی مشهد، مشهد، ایران
2 صالحه مهرآفرید، پزشک عمومی، دانشگاه علوم پزشکی مشهد، مشهد، ایران
چکیده
کلیدواژهها
عنوان مقاله [English]
نویسندگان [English]
Introduction
Urinary tract infections (UTIs) are a common infectious disease and a public health problem that imposes a large economic burden. Antibiotic resistance is rising among uropathogens and is a challenge for physicians. The aim of this study was to evaluate the epidemiology of antibiotic resistance in patients with community-acquired urinary tract infections leading to hospitalization in Imam Reza Hospital in Mashhad during 2019-2020.
Material and Methods
In this cross-sectional study, a sample of urine of patients admitted during 72 hours was collected and cultured by standard loop method in Blood Agar and McConkey Agar. After incubating; samples with colony count ≥ 105 CFU / ml of urine were considered as a positive culture. Then people were classified into different groups. Data were entered into SPSS software after allocating appropriate codes and analyzed.
Results
Among 416 samples; 249 ones were positive cultured; %86.8 of the bacteria were gram-negative. %50.6 of the positive cultures were Escherichia coli, followed by Candida, Pseudomonas aeruginosa and Klebsiella pneumoniae respectively. The most common gram-positive organism was Enterococcus. Resistance to at least one antibiotic was found in 91% of cases. Escherichia coli strains were most resistant to cefotaxime, ceftazidime, cotrimoxazole and ciprofloxacin. The highest sensitivity was observed to the amikacin.
Conclusion
There is no significant difference between the different groups in terms of the prevalence of urinary pathogens and common pathogens in the general population. The most effective antibiotics for the treatment of bacterial urinary tract infections are amikacin, nitrofurantoin, gentamicin, imipenem and meropenem.
کلیدواژهها [English]
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