بررسی تظاهرات بالینی، شیرخواران 2تا18 ماه با احتمال آلرژی به پروتئین شیرگاو ، روش های متداول در درمان و میزان پاسخ به درمان

نوع مقاله : مقاله پژوهشی

نویسندگان

1 گروه آمار زیستی، دانشکده بهداشت، دانشگاه علوم پزشکی همدان، همدان، ایران.

2 گروه اطفال، دانشگده پزشکی، دانشگاه علوم پزشکی زنجان، زنجان ، ایران

3 کمیته تحقیقات دانشجویی، دانشکده پزشکی ، دانشگاه علوم پزشکی زنجان، زنجان ، ایران

چکیده

مقدمه:
حساسیت به پروتئین شیرگاوی بدون درمان باعث ایجاد مشکلاتی از جمله عدم رشد کافی در قد و وزن کودکان شود. مطالعه حاضر با هدف مقایسه 4 نوع رژیم درمانی در حساسیت به پروتئین شیر گاو انجام شد.
روش بررسی :
در این مطالعه مقطعی به روش نمونه گیری تمام شماری از 50 شیرخوار مبتلا به تشخص حساسیت به پروتئین شیر گاوی که به درمانگاه اطفال مراجعه کرده اند بوده است .میزان پاسخ به رژیم های درمانی شامل حذف لبنیات از رژیم غذایی مادر فرمولای نیمه هیدرولیز شده،فرمولای کاملا هیدرولیز شده و فرمولا بر پایه آمینو اسید در کودکان مورد ارزیابی قرار گرفت. ابزار ردآوری یک چک لیست بر اساس بررسی متون و تحت نظر یک نفر فوق تخصص گوارش اطفال تهیه و تجزیه و تحلیل در نرم افزار spss19 انجام شد.
نتایج:
در این بررسی شایعترین یافته های مراجعه به پزشک مربوط به خونریزی گوارشی 31(68 درصد)،درماتیت14 (28 درصد) بود. میزان پاسخ به درمان های مختلف به ترتیب برای حذف لبنیات از رژیم مادر6 (12درصد) ، فرمولای نیمه هیدرولیز شده2 (4درصد)،فرمولای کاملا هیدرولیز شده8( 14درصد)و فرمولای برپایه آمینو اسید34 (68 درصد)بود.
نتیجه گیری:
شایعترین یافته در شیرخواران مبتلا به آلرژی به پروتئین شیر گاو مراجعه کننده به درمانگاه فوق تخصصی گوارش کودکان خونریزی گوارشی بود و بهترین پاسخ های درمانی به فرمولا بر پایه اسید آمینه بوده است.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

Evaluation of clinical manifestations of infants 2 to 18 months with the possibility of allergy to cow's milk protein referred to the gastrointestinal clinic and common methods of treatment and response to treatment

نویسندگان [English]

  • zahra Rostami 1
  • Mohammad Esagh Rozeh 2
  • MARYAM RASOLI 3
1 Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran.
2 Assistant Professor of Pediatrics Gastroenterology Department of Pediatrics, School of Medicine Ayatollah Mousavi Hospital Zanjan University of Medical Sciences, Zanjan, Iran
3 Student Research Committee, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
چکیده [English]

Background:
Allergy to cow's protein without treatment can cause problems such as insufficient growth in height and weight of children. The present study was conducted with the aim of comparing 4 types of treatment regimens in cow's milk protein sensitivity.
Method:
In this cross-sectional study, a total number of 50 infants with cow's milk feeding syndrome who referred to the pediatric clinic were selected. The rate of response to therapeutic regimens, including the elimination of dairy from the mother's diet, semi-hydrolyzed formula, fully hydrolyzed formula, and the amino acid-based formula was evaluated in children. The tool for compiling a checklist was prepared based on the literature review and under the supervision of a specialist in pediatrics. The analysis was done in spss19 software.
Results:
In this study, the most common findings of visiting a doctor were 31 (68 %) gastrointestinal bleeding, and 14 (28 %) dermatitis. The rate of response to different treatments was 6 (12%), semi-hydrolyzed formula 2 (4%), fully hydrolyzed formula 8 (14%), and formula based on amino acids 34 (68%), respectively, to remove dairy products from the mother's diet.
Conclusion:
The most common finding in infants with cow's milk protein allergy referred to a pediatric gastroenterology clinic was gastrointestinal bleeding, and the best treatment responses were to the formula based on amino acids.

کلیدواژه‌ها [English]

  • allergy
  • cow`s milk protein
  • treatment

مراجع

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مجله دانشکده پزشکی دانشگاه علوم پزشکی مشهد
دوره 65، شماره 6
بهمن و اسفند 1401
صفحه 2268-2272

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