نوع مقاله : مقاله پژوهشی
1 گروه علوم آزمایشگاهی، دانشکده علوم پزشکی سیرجان، سیرجان، ایران
2 استادیار گروه انگل شناسی و قارچ شناسی، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.
3 استادیار گروه علوم آزمایشگاهی ،واحد زاهدان،دانشگاه آزاد اسلامی، زاهدان، ایران
4 دانشکده علوم پزشکی سیرجان-سیرجان-ایران
عنوان مقاله [English]
Introduction: Human toxocariasis is a parasitic disease caused by the larvae of Toxocara canis (T. canis) and can cause many clinical complications in the liver, lungs, eyes, brain and kidney. Despite its significant effect on high-risk groups (people with reduced immune system), this parasite is usually ignored. The present study was conducted with the aim of investigating the serum prevalence and risk factors of toxocariasis in diabetic patients and hemodialysis patients in Zahedan (southeast of Iran).
Methods: This study was conducted in Sistan and Baluchistan province, Zahedan city with 400 diabetic and hemodialysis patients. A clot sample was taken to perform the ELISA test along with a questionnaire containing demographic information. All serum samples were tested for the presence of IgG antibodies against Toxocara species by ELISA serology method. Data analysis was done using SPSS version 22 software and descriptive statistics and chi-square test
Results: The prevalence of serum toxocariasis in diabetic and hemodialysis patients was reported as 2.8% and 3.5%, respectively. Among the variables of the study, contact with dogs and cats in the group of diabetic patients (OR=11.60 –% 95CI: 2.80-48.06). and in the group of hemodialysis patients contact with cats and dogs (OR=0.85- %95CI: 0.70-1.02) and blood group had a significant relationship with the prevalence of toxocariasis. P value ≤ 0.05.
Conclusion: Considering the few studies in the world, more epidemiological studies are needed to understand that diabetes and the hemodialysis process can be introduced as a factor in toxocariasis.