مروری بر تاثیر تمرینات ورزشی و مکمل‎های آنتی اکسیدانی در بیماران مبتلا به آسم

نوع مقاله : مقاله مروری

نویسندگان

1 دانشیار، گروه فیزیولوژی ورزشی، دانشگاه شهید مدنی آذربایجان، تبریز، ایران

2 استاد گروه فیزیولوژی ورزشی دانشگاه محقق اردبیلی، اردبیل، ایران

3 دکتری فیزیولوژی ورزشی دانشگاه محقق اردبیلی، اردبیل، ایران

4 دانشجوی کارشناسی ارشد فیزیولوژی ورزشی دانشگاه شهید مدنی آذربایجان، تبریز، ایران

چکیده

مقدمه
آسم یک بیماری التهابی مزمن است که با علائم تنفسی، انسداد متغیر راه هوایی، واکنش بیش از حد راه هوایی و التهاب راه هوایی مشخص می‎شود. برای بهبود این بیماری از تمرینات ورزشی و مکمل‎های آنتی اکسیدانی می‎توان استفاده کرد. در تحقیق حاضر مروری به تاثیر تمرینات ورزشی و مکمل‎های آنتی اکسیدانی در بیماران مبتلا به آسم پرداخته شده است.
روش کار
با استفاده از چندین پایگاه اطلاعاتی مشتمل Google Scholar، Web of Science، Science Direct، Pupmed، Scopus  و با استفاده از عناوین بیماری آسم و نام انواع آنها و اسامی مرتبط برای کلید واژه‎های بیماری آسم تا سال 2022 جستجو صورت گرفت. در ابتدا با محدود کردن جستجو، مطالعات غیر مرتبط و تکراری حذف، و پس از بررسی عناوین، چکیده ها و متون کامل غربالگری و مطالعات مناسب به تحقیق حاضر وارد شدند.
 نتیجه گیری
با تمرکز بر مطالعاتی که به نقش تاثیرات تمرینات ورزشی و مکمل‎های آنتی اکسیدانی در بیماران مبتلا به آسم پرداختند می‎توان گفت که ورزش در این بیماران از طریق مکانیسم‎های پاتوفیزیولوژیکی توانسته است در کاهش اثرات مضر بیماری آسم ایفای نقش کنند. به طوری که تمرینات منظم هوازی و تنفسی  در بهبود این بیماری توصیه شده است. همچنین بافت ریه بیماران مبتلا به آسم به دلیل تولید گونه‎های فعال اکسیژن و نیتروژن در معرض استرس اکسیداتیو قرار دارد. به همین دلیل با در نظر گرفتن کاهش آنزیم‎های آنتی اکسیدانی افزایش آپوپتوز، ریزش سلول‎های اپیتلیال راه هوایی و کاهش بازسازی راه هوایی را شاهد خواهیم بود. لذا مطالعات به نقش مثبت مصرف آنتی اکسیدان ها در بیماران مبتلا به آسم اشاره کرده اند.

کلیدواژه‌ها

عنوان مقاله [English]

A review of the effect of exercise training and antioxidant supplements in patients with asthma

نویسندگان [English]

  • Bahloul Ghorbanian 1
  • Marefat Siahkouhian 2
  • Afshin Rahbarghazi 3
  • Mohamadhadi Asghari 4
1 Associate Professor, Department of Sport Sciences, Faculty of Education and Psychology, Azarbaijan Shahid Madani University, Tabriz. Iran.
2 Professor, Department of Physical Education and Sport Sciences, Faculty of Education and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran.
3 Ph.D Exercise Physiology, Faculty of Education and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran.
4 Master of Exercise Physiology, Faculty of Education and Psychology, Azarbaijan SHahid Madani University, Tabriz, Iran.
چکیده [English]

Introduction: Asthma is a chronic inflammatory disease characterized by respiratory symptoms, variable airway obstruction, airway hyperresponsiveness, and airway inflammation. In the present study, a review of the effect of exercise and antioxidant supplements in patients with asthma has been discussed.
Materials and Methods: Using several databases including Google Scholar, Web of Science, Science Direct, PubMed, and Scopus, and using the titles of asthma and the names of their types and related names for the keywords of asthma until 2022, a search was made. At first, by limiting the search, irrelevant and repeated studies were removed, and after reviewing the titles, abstracts, and full texts, suitable studies were included in the current research.
Conclusion: Focusing on studies that focused on the effects of exercise and antioxidant supplements in patients with asthma, it can be said that exercise in these patients through pathophysiological mechanisms has been able to play a role in reducing the harmful effects of asthma. So that regular aerobic and breathing exercises are recommended to improve this disease. Also, the lung tissue of asthmatic patients is exposed to oxidative stress due to the production of reactive oxygen and nitrogen species. For this reason, taking into account the reduction of antioxidant enzymes, we will see an increase in apoptosis, the loss of airway epithelial cells, and a decrease in airway regeneration. Therefore, studies have pointed to the positive role of antioxidants in patients with asthma.

کلیدواژه‌ها [English]

  • Exercises
  • Patients with asthma
  • Vitamins
  • Melatonin
  • Selenium
  • Glutathione
  • Cysteine
  • Coenzyme Q10
  • Green tea

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مجله دانشکده پزشکی دانشگاه علوم پزشکی مشهد
دوره 65، شماره 6
بهمن و اسفند 1401
صفحه 2405-2429

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