تاثیر مصرف سیر و توت سیاه(شاه توت) همراه با تمرین هوازی بر فشار خون و کیفیت زندگی در بیماران مبتلا به هیپرتانسیون

نوع مقاله : مقاله پژوهشی

نویسندگان

1 کارشناس ارشد تغذیه ورزشی، گروه تغذیه ورزشی، دانشکده علوم اجتماعی، دانشگاه غیرانتفاعی رجاء، قزوین، ایران

2 استادیار گروه تغذیه ورزشی، دانشکده علوم اجتماعی، دانشگاه غیرانتفاعی رجاء، قزوین، ایران

3 استادیار، گروه تغدیه، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی، قزوین، ایران

4 دکتری فیزیولوژی ورزشی دانشگاه محقق اردبیلی، اردبیل، ایران

چکیده

بنابراین هدف این تحقیق بررسی تاثیر مصرف سیر و توت سیاه (شاه توت) همراه با تمرین هوازی بر فشار خون و کیفیت زندگی در بیماران مبتلا به هیپرتانسیون بود.

48 نفر از انها که در سه ماه اخیر هیچ گونه فعالیت ورزشی نداشتند، انتخاب شدند. وضعیت آزمودنی های تحقیق به لحاظ میزان کیفیت زندگی از طریق پرسشنامه کیفیت زندگی سازمان جهانی بهداشت و فشار خون در شرایط آزمایشگاهی محاسبه گردید و در نهایت در چهار گروه 12 نفره، تمرین هوازی و مصرف سیر، تمرین هوازی و مصرف توت سیاه، و تمرین هوازی و گروه کنترل تقسیم شدند. سپس متغیرهای مداخله گر اعم از تمرین هوازی(شامل 10 دقیقه گرم کردن، 25 تا 45 دقیقه راه رفتن – دویدن و تمرینات جنبشی با شدت 65 تا 75 درصد ضربان قلب بیشینه و 5 دقیقه سرد کردن) و مکمل دهی سیر(شکل کپسول های 1250 میلی گرمی، محصول شرکت نیچر مد روزانه دوعدد همراه وعده غذایی) و توت سیاه(به شکل کپسول میلی گرمی روزانه یک عدد) به مدت شش هفته بر روی آنها اعمال گردید و در پایان شش هفته مجددا فاکتورهای کیفیت زندگی و فشار خون اندازه‌گیری شد.
نتایج
نتیجه تحقیق نشان داد که فشار خون سیستولی در گروه تمرین هوازی و مصرف سیر به طور معنی داری کاهش یافته است (05/0P˂).
نتیجه‌گیری
بطور‌کلی به‌نظر می‌رسد تمرینات هوازی به همراه مکمل دهی سیر و توت سیاه بتوانند با اثرگذاری بر عوامل موثر بر کمپلیانس عروقی و نیز فاکتورهای مرتبط با گلیکوزیلاسیون باعث کاهش فشارخون و سختی‌عروقی شود

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The effect of consuming garlic and blackberry along with aerobic exercise on blood pressure and quality of life in hypertensive patients.

نویسندگان [English]

  • Farzaneh Ziaeian 1
  • Zohre Eskandari 2
  • Mohammad Reza Shiri-Shahsavar 3
  • Afshin Rahbarghazi 4
1 MSc. in sports nutrition, Department of Sports nutrition, Faculty of Social Sciences, Raja University, Qazvin, Iran
2 Assistant Professor, Department of Sports nutrition, Faculty of Social Sciences, Raja University, Qazvin, Iran
3 Assistant Professor, Department of Nutrition, Faculty of Nursing and Midwifery, Qazvin University of Medical Sciences, Qazvin, Iran
4 Ph.D Exercise Physiology, Faculty of Education and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran
چکیده [English]

Therefore, the aim of this research was to investigate the effect of garlic and blackberry consumption along with aerobic exercise on blood pressure and quality of life in patients with hypertension.

48 of them who did not do any sports activities in the last three months were selected. The condition of the research subjects in terms of quality of life was calculated through the quality of life questionnaire of the World Health Organization and blood pressure in laboratory conditions, and finally in four groups of 12 people, aerobic exercise and garlic consumption, aerobic exercise and blackberry consumption, and aerobic exercise and the control group were divided. Then the intervening variables, including aerobic exercise (including 10 minutes of warming up, 25 to 45 minutes of walking-running and kinetic exercises with an intensity of 65 to 75% of the maximum heart rate and 5 minutes of cooling down) and garlic supplementation (1250 capsules form) Milligram, the product of Nature Mod Company (two units daily with meals) and black mulberry (in the form of one milligram capsule daily) were applied to them for six weeks, and at the end of six weeks, quality of life factors and blood pressure were measured again.

The result of the research showed that the systolic blood pressure was significantly reduced in the group of aerobic exercise and garlic consumption (P˂0.05).

In general, it seems that aerobic exercises along with garlic and blackberry supplementation can reduce blood pressure and vascular stiffness

کلیدواژه‌ها [English]

  • Aerobic exercise
  • Garlic supplement
  • Blackberry supplement
  • Blood pressure
  • Quality of life

مراجع

  1.  

    1. Hambrecht R, Gielen S. Essay: Hunter-gatherer to sedentary lifestyle. The Lancet. 2005;366:S60-S1.
    2. Hussain A, Claussen B, Ramachandran A, Williams R. Prevention of type 2 diabetes: a review. Diabetes research and clinical practice. 2007;76(3):317-26.
    3. Baster-Brooks C, Baster T. Exercise and hypertension. Australian family physician. 2005;34(6).
    4. Alpsoy Ş. Exercise and hypertension. Physical Exercise for Human Health. 2020:153-67.
    5. Gabb G. What is hypertension? Australian Prescriber. 2020;43(4):108.
    6. Oliveros E, Patel H, Kyung S, Fugar S, Goldberg A, Madan N, Williams KA. Hypertension in older adults: Assessment, management, and challenges. Clinical cardiology. 2020;43(2):99-107.
    7. Litwin M, Kułaga Z. Obesity, metabolic syndrome, and primary hypertension. Pediatric Nephrology. 2021;36:825-37.
    8. Katsimardou A, Imprialos K, Stavropoulos K, Sachinidis A, Doumas M, Athyros V. Hypertension in metabolic syndrome: novel insights. Current Hypertension Reviews. 2020;16(1):12-8.
    9. Beevers G, Lip GY, O'Brien E. The pathophysiology of hypertension. BMJ (Clinical research ed). 2001;322(7291):912-6.
    10. Messerli FH, Williams B, Ritz E. Essential hypertension. The Lancet. 2007;370(9587):591-603.
    11. Rahbarghazi A, Siahkouhian M, Bolboli L. Is consuming caffeine affect the blood pressure of swimmers? medical journal of mashhad university of medical sciences. 2018;61(1):847-52.
    12. Yoshinaga K, Beanlands RS, Dekemp RA, Lortie M, Morin J, Aung M, et al. Effect of exercise training on myocardial blood flow in patients with stable coronary artery disease. American Heart Journal. 2006;151(6):1324. e11-. e18.
    13. Hinderliter A, Sherwood A, Gullette EC, Babyak M, Waugh R, Georgiades A, Blumenthal JA. Reduction of left ventricular hypertrophy after exercise and weight loss in overweight patients with mild hypertension. Archives of internal medicine. 2002;162(12):1333-9.
    14. Whelton SP, Chin A, Xin X, He J. Effect of aerobic exercise on blood pressure: a meta-analysis of randomized, controlled trials. Annals of internal medicine. 2002;136(7):493-503.
    15. Tsai JC, Yang HY, Wang WH, Hsieh MH, Chen PT, Kao CC, et al. The beneficial effect of regular endurance exercise training on blood pressure and quality of life in patients with hypertension. Clinical and experimental hypertension. 2004;26(3):255-65.
    16. Hassan H, Abdel-Aziz A. Evaluation of free radical-scavenging and anti-oxidant properties of black berry against fluoride toxicity in rats. Food and chemical toxicology. 2010;48(8-9):1999-2004.
    17. Fernandez-Panchon M, Villano D, Troncoso A, Garcia-Parrilla M. Antioxidant activity of phenolic compounds: from in vitro results to in vivo evidence. Critical reviews in food science and nutrition. 2008;48(7):649-71.
    18. Arts IC, Hollman PC. Polyphenols and disease risk in epidemiologic studies. The American journal of clinical nutrition. 2005;81(1):317S-25S.
    19. Baba S, Osakabe N, Kato Y, Natsume M, Yasuda A, Kido T, et al. Continuous intake of polyphenolic compounds containing cocoa powder reduces LDL oxidative susceptibility and has beneficial effects on plasma HDL-cholesterol concentrations in humans. The American journal of clinical nutrition. 2007;85(3):709-17.
    20. Duffy SJ, Keaney Jr JF, Holbrook M, Gokce N, Swerdloff PL, Frei B, Vita JA. Short-and long-term black tea consumption reverses endothelial dysfunction in patients with coronary artery disease. Circulation. 2001;104(2):151-6.
    21. Pandey KB, Rizvi SI. Plant polyphenols as dietary antioxidants in human health and disease. Oxidative medicine and cellular longevity. 2009;2:270-8.
    22. Hassan HA, Yousef MI. Mitigating effects of antioxidant properties of black berry juice on sodium fluoride induced hepatotoxicity and oxidative stress in rats. Food and Chemical Toxicology. 2009;47(9):2332-7.
    23. Buljeta I, Pichler A, Šimunović J, Kopjar M. Polyphenols and antioxidant activity of citrus fiber/blackberry juice complexes. Molecules (Basel, Switzerland). 2021;26(15):4400.
    24. Reed J. Cranberry flavonoids, atherosclerosis and cardiovascular health. Critical reviews in food science and nutrition. 2002;42(S3):301-16.
    25. Erlund I, Koli R, Alfthan G, Marniemi J, Puukka P, Mustonen P, et al. Favorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol. The American journal of clinical nutrition. 2008;87(2):323-31.
    26. Skoczyñska A, Jêdrychowska I, Porêba R, Affelska-Jercha A, Turczyn B, Wojakowska A, Andrzejak R. Influence of chokeberry juice on arterial blood pressure and lipid parameters in men with mild hypercholesterolemia. Pharmacol Rep. 2007;59(Suppl 1):177-82.
    27. Lehtonen H, Suomela J, Tahvonen R, Vaarno J, Venojärvi M, Viikari J, Kallio H. Berry meals and risk factors associated with metabolic syndrome. European journal of clinical nutrition. 2010;64(6):614-21.
    28. Vendrame S, Adekeye TE, Klimis-Zacas D. The Role of Berry Consumption on Blood Pressure Regulation and Hypertension: An Overview of the Clinical Evidence. Nutrients. 2022;14(13):2701.
    29. Mizuno CS, Rimando AM. Blueberries and metabolic syndrome. Science, Engineering and Health Studies. 2009:7-17.
    30. Seeram NP. Berry fruits: compositional elements, biochemical activities, and the impact of their intake on human health, performance, and disease. ACS Publications; 2008. p. 627-9.
    31. Klepser TB, Klepser ME. Unsafe and potentially safe herbal therapies. American Journal of Health-System Pharmacy. 1999;56(2):125-38.
    32. Ried K, Frank OR, Stocks NP, Fakler P, Sullivan T. Effect of garlic on blood pressure: a systematic review and meta-analysis. BMC cardiovascular disorders. 2008;8:1-12.
    33. Bashiri J. The effect of regular aerobic exercise and garlic supplementation on lipid profile and blood pressure in inactive subjects. Zahedan Journal of Research in Medical Sciences. 2015;17(4).
    34. Aghababaee S, Vafa M, Shidfar F, Gohari M, Katebi D, Mohammadi V. Effect of black mulberry (Morus nigra L.) consumption on serum concentrations of lipoproteins, Apo-A1, Apo-B and hs-CRP and blood pressure in dyslipidemic patients. Iranian Journal of Nutrition Sciences & Food Technology. 2014;8(4):67-81.
    35. Fahima Mehrabani, Bahman Mirzai, Javad Mehrabani, Hossein Ghafouri. Effect of garlic extract supplementation and endurance exercise on salivary antioxidant enzymes and blood pressure in trained females. Journal of Applied Exercise Physiology. 2016: 12 (23):99-110.
    36. Tajalli P, Taghizadeh Shideh Z, Sadeghi Afjeh Z. Modeling Passion for Education Based on School Climate and Quality of Life for Students with Self-Regulating Mediation two-Parent Students. Iranian Journal of Educational Society. 2021;7(1):101-10.
    37. Aahedi Anaraki A, Khajei R, Rashid Lamir A, Barjasteh Yazdi A. The Effect of a Course of Aerobic-resistance Training and Ursolic Acid Consumption on Irisin Levels and Inflammatory Factors in Overweight Middle-aged Men. Journal of Animal Biology. 2021;14(1):81-91.
    38. Szulinska M, Gibas-Dorna M, Miller-Kasprzak E, Suliburska J, Miczke A, Walczak-Gałezewska M, et al. Spirulina maxima improves insulin sensitivity, lipid profile, and total antioxidant status in obese patients with well-treated hypertension: a randomized double-blind placebo-controlled study. European Review for Medical & Pharmacological Sciences. 2017;21(10).
    39. Wheeler MJ, Dunstan DW, Ellis KA, Cerin E, Phillips S, Lambert G, et al. Effect of morning exercise with or without breaks in prolonged sitting on blood pressure in older overweight/obese adults: Evidence for sex differences. Hypertension. 2019;73(4):859-67.
    40. Cornelissen VA, Fagard RH. Effects of endurance training on blood pressure, blood pressure–regulating mechanisms, and cardiovascular risk factors. Hypertension. 2005;46(4):667-75.
    41. Baross A, Kay A, Baxter BA, Wright B, McGowan C, Swaine IL. Effects of isometric resistance training and detraining on ambulatory blood pressure and morning blood pressure surge in young normotensives. Frontiers in physiology. 2022:1872.
    42. POULADI BB, BOGHRABADI V, HEJAZI SM. Comparison of the effect of aerobic training exercise and different intensities on duration of post-exercise hypotension in middle-aged women. 2015.
    43. Di Lorenzo C, Colombo F, Biella S, Stockley C, Restani P. Polyphenols and human health: The role of bioavailability. Nutrients. 2021;13(1):273.
    44. Swallah MS, Sun H, Affoh R, Fu H, Yu H. Antioxidant potential overviews of secondary metabolites (polyphenols) in fruits. International journal of food science. 2020;2020.
    45. Nemzer BV, Al-Taher F, Yashin A, Revelsky I, Yashin Y. Cranberry: Chemical composition, antioxidant activity and impact on human health: Overview. Molecules (Basel, Switzerland). 2022;27(5):1503.
    46. Stintzing FC, Carle R. Functional properties of anthocyanins and betalains in plants, food, and in human nutrition. Trends in food science & technology. 2004;15(1):19-38.
    47. Neto CC. Cranberry and blueberry: evidence for protective effects against cancer and vascular diseases. Molecular nutrition & food research. 2007;51(6):652-64.
    48. Mazza G. Anthocyanins and heart health. Annali-Istituto Superiore Di Sanita. 2007;43(4):369.
    49. Williams MJ, Sutherland WH, McCormick MP, Yeoman DJ, de Jong SA. Aged garlic extract improves endothelial function in men with coronary artery disease. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives. 2005;19(4):314-9.
    50. Imaizumi VM, Laurindo LF, Manzan B, Guiguer EL, Oshiiwa M, Otoboni AMMB, et al. Garlic: A systematic review of the effects on cardiovascular diseases. Critical reviews in food science and nutrition. 2023;63(24):6797-819.
    51. Varade S, Nadella M, Hirake A, bhausaheb Mungase S, Ali A, Adela R. Effect of garlic on the components of metabolic syndrome: A systematic review and meta-analysis of randomized controlled trials. Journal of Ethnopharmacology. 2024;318:116960.
    52. Sawal SB, Thakre MP, Ganeshrao P. Review on effect of garlic (Allium Sativum) on blood pressure. 2021.
    53. Hemmati R, Dabbagh Nikukheslat S, Pourrahim Ghouroghchi A. The effect of acute endurance exercise after three different doses of garlic supplementation on coagulating factor VIII, fibrinogen and systolic and diastolic blood pressure in young athletic men. Daneshvar Medicine. 2021;28(5):63-74.
    54. Khatami Saravi SL, Abdi A, Barari A. Effect of aerobic training with Garlic consumption on matrix metalloproteinase-3, 9 and tissue inhibitor of metalloproteinase-1 in obese postmenopausal women with high blood pressure: A clinical trial study. Journal of Gorgan University of Medical Sciences. 2021;22(4):14-22.
    55. Rejeski WJ, Mihalko SL. Physical activity and quality of life in older adults. The Journals of Gerontology Series A: Biological sciences and medical sciences. 2001;56(suppl_2):23-35.
    56. Wikman A, Wardle J, Steptoe A. Quality of life and affective well-being in middle-aged and older people with chronic medical illnesses: a cross-sectional population based study. PloS one. 2011;6(4):e18952.
مجله دانشکده پزشکی دانشگاه علوم پزشکی مشهد
دوره 67، شماره 1
شماره فروردین-اردیبهشت1403
فروردین و اردیبهشت 1403
صفحه 103-115

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