بررسی اثر و مقایسه سه نوع تمرین ورزشی (تحریک الکتریکی عضلانی، هوازی و مقاومتی) بر بیان ژن‌های ACTN3 وACE در زنان دارای اضافه وزن

نوع مقاله : مقاله پژوهشی

نویسندگان

1 دانشجوی کارشناسی ارشد فیزیولوژی ورزشی گروه تربیت بدنی و علوم ورزشی، واحد مشهد، دانشگاه آزاد اسلامی، مشهد، ایران

2 استادیار گروه تربیت بدنی، دانشگاه آزاد اسامی واحد مشهد، مشهد، ایران

3 عضو هیات علمی دانشکده علوم ورزشی دانشگاه فردوسی مشهد

چکیده

مقدمه: امروزه با توجه به سبک زندگی و تغذیه ناسالم و بی‌تحرکی، افراد درگیر بیماری‌های مختلف مثل چاقی و اضافه وزن می‌شوند. هدف از پژوهش حاضر بررسی اثر و مقایسه سه نوع تمرین ورزشی (تحریک الکتریکی عضلانی، هوازی و مقاومتی) بر بیان ژن‌های ACTN3 (آلفا اکتنین 3) وACE (آنزیم مبدل آنژیوتانسین) در زنان دارای اضافه وزن بود.
روش‌شناسی: در این پژوهش نیمه تجربی تعداد 40 زن دارای اضافه وزن به شکل تصادفی در چهار گروه 10 نفرِ 1) تمرین EMS (تحریک الکتریکی عضلانی کل بدن) 2) تمرین استقامتی 3) تمرین مقاومتی 4) کنترل قرار گرفتند. آزمودنی‌های گروه‌های تمرینی به مدت هشت هفته به اجرای تمرینات منتخب مربوط به گروه خود پرداختند. 48 ساعت پیش و پس از اجرای تمرینات، نمونه‌ی خونی جهت سنجش بیان ژن‌های ACTN3 وACE جمع‌آوری شد. داده‌ها با استفاده از آزمون‌ تی همبسته، آنالیز واریانس یک‌طرفه و آزمون تعقیبی توکی در سطح معناداری کمتر از 05/0 تجزیه‌وتحلیل شد.
یافته‌ها: نتایج نشان داد که پس از هشت هفته مداخله؛ در گروه هوازی، مقاومتی و EMS مقادیر ACTN3 و ACE افزایش معناداری پیدا کرد. این درحالی‌که بود‌ که در هیچ‌کدام از این متغیرها در گروه کنترل اختلاف معناداری مشاهده نشد (05/0P>). همچنین نتایج آزمون تحلیل واریانس یک‌طرفه نشان داد که تمرین EMS باعث تغییرات بیشتری در بیان ژن‌های ACTN3 و ACE در مقایسه با دیگر پروتکل‌های پژوهش در زنان دارای اضافه وزن می شود (p<0.05).

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

Investigation of the effect and comparison of three types of exercise (muscular electrical stimulation, aerobic and resistance) on the expression of ACTN3 and ACE genes in overweight women

نویسندگان [English]

  • Romina Molae 1
  • mahmoud soltani 2
  • Amir Rashidlamir 3
1 MSc, Faculty of Physical Mashhad Branch, Islamic Azad University, Mashhad
2 .Iran, Mashhad, University Azad Islamic, Branch Mashhad, Education Physical of Department, Professor Assistant
3 5. Department of Sport Physiology, Faculty of Sport Sciences, Ferdowsi University of Mashhad, Mashhad, I.R.Iran
چکیده [English]

Introduction:
Nowadays, due to unhealthy lifestyle and diet and inactivity, people get involved in various diseases such as obesity, and overweight. The purpose of this study was to investigate and compare the effect of three types of exercise (muscular electrical stimulation, aerobic and resistance) on the expression of ACTN3 (Alpha-actinin-3) and ACE (Angiotensin-Converting Enzyme) genes in overweight women.
Methodology:
In this semi-experimental research, 40 overweight women were randomly divided into four groups of 10 people: 1) EMS training (electro-muscle stimulation), 2) endurance training, 3) resistance training, and 4) control. The subjects of the training groups performed the selected exercises related to their group for eight weeks. A blood sample was collected 48 hours before and after the training sessions to measure the expression of ACTN3 and ACE genes. Data were analyzed using correlated t-test, one-way ANOVA, and Tukey's post hoc test at a significance level of p<0.05.
Results:
The results showed that ACTN3 and ACE values increased significantly in the aerobic, resistance, and EMS groups after eight weeks of intervention. At the same time, there was no significant difference in any of these variables in the control group (P>0.05). Also, the results of one-way ANOVA showed that EMS training caused more changes in the expression of ACTN3 and ACE genes compared to other research protocols in overweight women (p<0.05).

کلیدواژه‌ها [English]

  • EMS
  • ACTN3
  • ACE
  • Resistance training
  • Endurance training

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مجله دانشکده پزشکی دانشگاه علوم پزشکی مشهد
دوره 67، شماره 2
خرداد-تیر1403
خرداد و تیر 1403
صفحه 435-450

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